Community

The core Israeli cell death community encompasses a few dozen research groups engaged in the exploration of the cellular and molecular mechanisms underlying the different pathways of cell death in all organisms. Local researchers utilize a variety of in vitro and in vivo systems and are involved in varied studies, ranging from exploration of the core cell death machineries, as well as tangential cellular processes associated with cell death components, through the uncovering of different roles of cell death in development, homeostasis and in the pathology of diseases, to translational studies aiming to utilize this knowledge to fight different disease (see the list of groups and topics).

Society Members

 Arama Eli 

Caspases without death and death without caspases in development.

Ariel Amiram

Apoptotic cell clearance and its consequences in inflammation and its resolution.

Benhar Moran

Redox signaling in inflammation and cancer.

Ben-Neriah Yinon 

Signaling of inflammation and cancer through genetically-modified mice

Ben-Yehuda Dina

The role of Livin in health and disease.

Burstyn-cohen Tal

The roles of TAM receptors and their ligands PROS1 and GAS6 in phagocytosis and inflammation in health and disease.

Engelberg-Kulka Hanna 

Program cell death in bacteria

Fishelson Zvi

Regulated necrotic cell death activated by pore-forming proteins: identification of positive and negative regulators.

Friedler Assaf

Interactions of cell death-related proteins, intrinsic disorder in cell death-related proteins, peptide inhibitors of cell death-related proteins.

Fuchs Yaron

The role of programmed cell death in stem cells.

Gerlic Mordechay​

Cell Death and Immune Response: Mechanisms of Necroptosis and Pyroptosis and their role in Inflammation.

Gerlitz Offer

Spatial and temporal regulation of cell fate determination, cell proliferation and cell death and survival during normal and aberrant organ formation.

Gopas Jacob​

Senescent cells in Hodgkin’s lymphoma.

Gottlieb Eyal

Metabolic vulnerabilities of cancer.

Gross Atan

Mitochondria in the center of cell fate decisions.

Kimchi Adi

The Protein Interaction Map of Programmed Cell Death in Development and Disease.

Krizhanovsky Valery 

Cellular senescence in aging, cancer and embryonic development.

Kurant Estee

Cell clearance mechanisms during development and aging.

Larisch Sarit

Molecular mechanisms of cell death and cancer​.​

Livneh Etta

Signal transduction in cancer – the response to stress and chemotherapy by protein kinases and upstream open reading frames (uORFs)-encoded peptides.​

Melloul Danielle

Mechanisms involved in pancreatic beta cell death in diabetes.​

Mevorach Dror

Autoimmunity, immune deficiency and autoinflammatory conditions related to huaman mutations affecting cell death and clearance of dying cells.

Oren Moshe

Functional analysis of the p53 and Hippo pathways.

Sagi Irit

A multidisciplinary approach to study the extracellular matrix.

Shoshan-Barmatz Varda

Uncovering the function of the mitochondrial protein VDAC1 in the regulation of cell life and death.

Stein Reuven 

Canonical and non-canonical actions of Bcl-2 family proteins

Toledano Hilla

Tissue regeneration, adult stem cells and aging using Drosophila model organism.

Wallach David

Signaling for cell death and for cell survival mechanisms by the TNF cytokine family.

Yaron Avraham

Investigating the cellular and molecular mechanisms that control the wiring of the nervous system.