The core Israeli cell death community encompasses a few dozen research groups engaged in the exploration of the cellular and molecular mechanisms underlying the different pathways of cell death in all organisms. Local researchers utilize a variety of in vitro and in vivo systems and are involved in varied studies, ranging from exploration of the core cell death machineries, as well as tangential cellular processes associated with cell death components, through the uncovering of different roles of cell death in development, homeostasis and in the pathology of diseases, to translational studies aiming to utilize this knowledge to fight different disease (see the list of groups and topics).